Not all deadly poisons available to the ancient poisoner came from plant sources. Cantharidin is a substance emitted from several species of the blister beetle, sometimes known as Spanish Fly. In The Well of Urd, the courtesan Cyra buys a vial of it and quietly pockets a vial of aconite, with the intention of placing both in a cosmetic cream for her intended target. From her conversation with the apothecary, it is clear this is not the first time she has made this purchase:
Only once had she purchased the scarlet bottle. She had sworn she never would again. Yet now she lifted her finger and pointed to it. His teeth flashed in a sardonic laugh. “Oho! Little Cyra seeks to lift the members of her male companions. If I recall that did not go so well last time you tried it. Perhaps you may wish to reconsider?” Nevertheless he pulled the little tear drop bottle from its resting place in the wooden rack next to its companions. “Blister beetle.” He chuckled and swirled the liquid around and watched the light catch the deep red of the bottle. “So many men so eager to try it. In low enough doses it make them stand as stiff and tall as a wooden post. They pleasure the ladies all night.” He leered at her. “And when they finally can come down, hours later, they spend days pissing blood. Is that not what happened to the vestarches you entertained last year?” He laughed when she grimaced. “It is over and done. He was a fool and should have known better. He was lucky. Some die from the elixir of the blister beetle. Yet you will purchase it again?”
Yet Cyra does purchase it again. With such a risk at ingesting it, what made anyone desparate enough to try it? Cathardin, is a burn agent, potent enough to cause the skin to raise in painful blisters and dangerous enough to actually burn the insides of those foolish enough to ingest it. The Marquis de Sade was reported to have been put on trial for the death of two prostitutes to whom he gave cathardin-laced pastilles. It was his intention that the prostitutes would fall into his amorous embrace due to the supposed aphrodisiac nature of the poisonous pastilles. Instead they both died agonizing deaths, hardly a sexy way to end the evening.
Due to the fact that is odorless and colorless it no doubt made a wonderful candidate for the repertoire of the especially fiendish poisoner. Because of the vesicating nature of the chemical, it was ideal to use dermally as well. This was the very plan Cyra had in mind as the cathardin would open up the skin, making way for the even deadlier aconite. Typically, it takes twenty-four to forty-eight hours for the blisters to emerge on the skin, eventually rupturing and leaving something akin to second degree burns.

Taken internally, it literally burns the interior of the gastrointestinal and genitourinary tract. By those intending to use its doubtful aphrodisiac properties, the intention is to cause priapism of the penis, from genitourinary irritation engorging it with blood and serving as a sort of primitive Viagra. However, the intended erection turns out to be unpleasant and even painful and when finally flaccid, results in painful and bloody urination for some time after, assuming the unwary experimenter lives. There are many accounts of death from ingestion of catharidin. It was as feared as many of its more famous counterparts in poison. So much so that Byzantine law heavily regulated them. The Digest of Roman Law, compiled by the Eastern Roman Emperor Justinian in the 6th century CE, clearly states in regards to murders and poisoners:
It is laid down by another decree of the senate that dealers in cosmetics are liable to the penalties of this law (the Lex Cornelia on murderers and poisoners) if they recklessly hand over to anyone hemlock (cicuta), salamander, aconite, pine-worms (pitupcampae) [a caterpillar with extremely irritating hairs] or buprestis [a species of blister beetle], mandragora [mandrake] or, except for the purposes of purification, catharsis beetle.
Brackets mine for the purposes of clarification.
Whether such laws applied to every part of the empire, even in as far-flung areas as Roman occupied Antioch, my research failed to unearth. It is reasonable to assume that at the very least, apothecaries selling such substances would be wary that charges might be brought against them, should their merchandise happen to be the cause of death of anyone with litigious relatives. The one purchasing such items also had no guarantee that said items were everything an apothecary claimed they were. Then, as now, caveat emptor. The very real danger in cathardin as it is today, is that there is no antidote. Unlike poisons such as aconite which operate on the body with toxic alkaloids and therefore have an antidote, cathardin is corrosive and is akin to ingesting or touching battery acid. It destroys the tissues it comes in contact with. It is, as it was in Byzantine time, heavily regulated and for good reason. Few doctors in the U.S. use cathardin for wart and tattoo removal any longer, preferring salicylic acid and liquid nitrogen instead. Its use has almost been made a joke of in popular culture. But as we have seen, the blister beetle and its deadly elixir was certainly no joke at all.
Resources:
“BOOK FORTY-EIGHT.” In The Digest of Justinian, Volume 4, edited by WATSON ALAN, 309-77. University of Pennsylvania Press, 1998. http://www.jstor.org/stable/j.ctt3fh9jv.12.
Medical Toxicology of Natural Substances: Foods, Fungi, Medicinal Herbs, Plants and Venomous Animals by Donald G. Barceloux 2012
The American Dispensatory, Containing the Natural, Chemical and and Pharmaceutical and Medical History of Different Substances Employed in Medicine by John Redman Coxe 1831
Cantharidin. (2018, January 16). In Wikipedia, The Free Encyclopedia. Retrieved 13:53, January 20, 2018, from https://en.wikipedia.org/w/index.php?title=Cantharidin&oldid=820699738
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immunity to belladonna as related in George Buchanna’s History of Scotland, vol 6:
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Poison! Just the word would cause a medieval citizen of Constantinople to cast a furtive glance into his or her cup. Almost all the poisons available to the people of the Middle Ages were derived from plants. Not all who were suspected of dying of poison, necessarily did so, but it is a testament to how common it was and much the danger was ever present on the mind of especially upper class Byzantines.
Of the ones we will talk about in this series, most notorious is Aconitum, among many other names also known as Monk’s Hood, Wolfsbane (for its reputation in poisoning wolves) and Queen of Poisons. It belongs to the family Ranunculaceae, including over 250 species. The Byzantines would have been very familiar with this deadly poison, dubbing it lykotonon — “wolf slaying”. Historically, Cleopatra VII of Egypt was said to have poisoned her brother Ptolemy XIV with aconite. In classical mythology, the sorceress Medea attempted to have king Aegeus unwittingly kill his own son, Theseus with a cup poisoned with aconite. It is said to have sprung from the spittle of Cerberus, famed three-headed dog of Greek myth. Even touching this deadly plant, especially the roots, can gain you an unpleasant death.
A case has been made for the fly agaric mushroom. Despite the fact that this red fungus, speckled with white shows up in almost every European fairy tale picture book you ever read as a child, it grew in Europe in only isolated areas. It certainly does not grow in Iceland where there is much mention of the berserkers. Furthermore, the effects of the mushroom, unless used very carefully, are more likely to produce real illness than the desired level of hallucination in those who ingest it. The potency of the mushroom is affected by many things: the time of the year it is harvested, where it has been harvested and how it is collected. There is not enough uniformity to produce the desired outcome.
Icelandic Egil’s Saga whose father Skallagrim was a berserker and the son of Kveldulf Bjalfson or Evening Wolf, also a berserker. This very much indicates the condition was genetic and places some weight on its being something like IED which we have today.
“There was a man named Ulf, son of Bjalf… Ulf was a man so tall and strong that none could match him and in his youth he roved the seas as a freebooter….he was a berserker.” Egil’s Saga.
Dessert is an apt conclusion to the series on food. Desserts, including sweetmeats and honey cakes were eaten by the higher classes, including koptoplakous, the ancestor to baklava still eaten in Greece today. It would have certainly been on Theophana’s table:
The ambassador, Liutprand of Cremona mentioned in a previous post who objected to garum, also did not care for Byzantine wine which he described as “mixed with pitch, resin, and plaster was to us undrinkable”. Perhaps the ambassador was merely difficult to please. He must have been alone in his assessment, as Byzantine wines were much favored by Western Europeans. He may have been referring to Retsina, a type of wine that got its unique flavor from sealing the wine jars with pine resin.
Vegetables were eaten by citizens of the Eastern Roman Empire and in a wide variety. Most of them were well know to the modern diet, such as cabbage, carrots and greens. Artichokes were well known and Antioch was famous for its cucumbers. Melons were cheap and readily available. Lentils were a staple in the diet of the poor. Those that could afford them seasoned their food with spices, some brought in from Asia. These included cinnamon, caraway, cardamom, cumin, ginger, nutmeg, saffron, pepper, clove, coriander, among many others that can still be find in our spice cabinets today, though now far more easily and cheaply obtained. Those with less money would use onions, leeks and garlic for seasoning their food. Eggs were favored by all classes and came from hens, geese and pheasants. The Byzantine omelet known as the sphoungata was stuffed with olives and goat cheese and perhaps chickpeas salted and cooked in olive oil. It would even have been on the table of the Emperor himself as mentioned in The Serpentine Key: